Pancreas Cancer Incidence and Pancreas Cancer-Associated Mortality Are Low in National Cohort of 7211 Pancreas Cyst Patients

Pancreas and cyst segmentation

Accurate segmentation of abdominal organs from medical images is an essential part of surgical planning and computer-aided disease diagnosis. Many existing algorithms are specialized for the segmentation of healthy organs. Cystic pancreas segmentation is especially challenging due to its low contrast boundaries, variability in shape, location and the stage of the pancreatic cancer. We present a...

Cancer of the pancreas.

The malignant growth may originate either in the duct cells or acini of the gland, or in the islets of Langerhans. Cancer of the islet cells is uncommon and is discussed in a later section. About 80% of tumours are adenocarcinomas which arise from ductular epithelium. The neoplasm is hard and scirrhous and the cells are columnar or cuboidal with clear-cut cellular outlines. Cancers arising from...

Exocrine pancreas cancer

The pancreas cancer microenvironment.

Pancreatic ductal adenocarcinoma (PDA) is a common and lethal malignancy resulting in more than 250,000 deaths per year worldwide. Despite extensive efforts, cytotoxic and targeted therapies have provided only limited efficacy for patients with PDA to date. One contributing factor to the failure of systemic therapies may be the abundant tumor stromal content that is the characteristic of PDA. T...

Borderline and Unresectable Pancreas Cancer

Expert Panel on Radiation Oncology–Gastrointestinal: William Small Jr, MD; John P. Hayes, MD; W. Warren Suh, MD, MPH; May Abdel-Wahab, MD, PhD; Ross A. Abrams, MD; Nilofer Azad, MD; Prajnan Das, MD; Jadranka Dragovic, MD; Karyn A. Goodman, MD; Salma K. Jabbour, MD; William E. Jones III, MD; Andre A. Konski, MD, MBA, MA; Albert C. Koong, MD, PhD; Rachit Kumar, MD; Percy Lee, MD; Timothy M. Pawli...